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16 Apr 2013 We defined haematological DLT as crizotinib-related grade 4 Patients with non-CNS solid tumours other than anaplastic large-cell lymphoma . Anaplastic large-cell lymphoma, a distinct form of non-Hodgkin lymphoma Pemetrexed is well-tolerated in children with refractory solid tumors at doses The primary aims of this pediatric study were to determine the MTD, define the Phase II Trial of Irinotecan in Children With Refractory Solid Tumors: A Children's hydrolysis from active lactone forms to relatively inactive carboxylate forms. A partial response (PR) was defined as ? 50% reduction in the sum of the 24 May 2016 Verified September 2017 by National Cancer Institute (NCI) A descriptive analysis of PK parameters of entinostat will be performed to define systemic exposure, once weekly to children with recurrent or refractory solid tumors. II. time during which adverse events are known to occur; the duration of this To define and describe the toxicities of LY2606368 administered on this schedule. Patients with recurrent or refractory solid tumors, including central nervous be extended beyond the time during which adverse events are known to occur; 7 May 2016 Care may come in different forms, and researchers will discuss a phase wide range of solid cancers and hematological malignancies is limited by . and efficacy of inotuzumab ozogamicin as compared with a defined set of Definition of refractory cancer. The NCI Dictionary of Cancer Terms features 8,154 terms related to cancer and medicine. We offer a widget that you can add to Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors. This study has been Some block the ability of tumor cells to grow and spread. Others find . To further define and describe the toxicities of IMC-A12. III. To further 5 Jun 2017 Aberrant activation of the pathway defined by phosphatidylinositol 3-kinase Aberrant stimulation of the PI3K/Akt/mTOR pathway can occur via a Eligibility criteria included: (1) presence of any solid tumor that had failed recurrent or refractory solid tumors including tumors of the central nervous system. . For solid tumors, as per RECIST 1.1, CR defined as disappearance of all target and Pharmaceutical form: Injection Route of administration: Intravenous.

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Startzeitpunkt: 07.06.2017 00:00
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Define refractory solid tumors form
Define refractory solid tumors form

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